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If the side chain $\mathrm pK_\mathrm a$ were lower than $9.11$, then you should average the carboxyl and side chain $\mathrm pK_\mathrm a$'s instead

Gonadal steroids exert facilitating and buffering effects on glucocorticoid-mediated transcriptional regulation of corticotropin-releasing hormone and corticosteroid receptor genes in rat brain

Insert the needle at a 45 to 90-degree angle into the pinched skin

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