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This specific binding mode of optimized DEL7 analogs to the 3CL protease is different from all other current benchmark SARS-CoV-2 3CL protease non-covalent inhibitors, as demonstrated by the clear difference of 29 in a structural overlay of 3CL bound to it and other non-covalent inhibitors (Supplementary Fig

Our results underlined that the functions of glutathione-metabolic proteins could be dependent on strain backgrounds and morphological forms

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