bacterial and host-derived glutathione are required to activate prfa New roles for glutathione: Modulators of virulence pathogenesis Glutathione metabolism impacts fungal virulence
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Yang, X., Chang, Y
The HHxxxDG motif promotes the condensation reaction and transfer of the intermediate to the downstream PCP, with the second His thought to be central for the catalytic activity of the C domain 12
discovered that administration of imidazole ketone erastin (IKE), a ferroptosis inducer, could mitigate synovitis and prevent joint destruction (133)
doi: 10.1002/ana.10277 154
Cell 121: 10591069 MeyerAJ,BrachT,MartyL,KreyeS,RouhierN,JacquotJP,HellR (2007) Redoxsensitive GFP in Arabidopsis thaliana is a quantitative biosensor for the redox potential of the cellular glutathione redox buffer
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