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Br J Cancer 84 : 1118 Ford HER, Mitchell F, Cunningham D, Farrugia DC, Hill ME, Rees C, Calvert AH, Judson IR, Jackman AL (2002) Patterns of elevation of plasma 2-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331

Because most of the samples studied were from children, it is unlikely that smoking confounds our meta-analytic results, but effects of obesity on oxidative stress cannot be ruled out

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In this case, a gastric/duodenal ulcer should be excluded

Understanding both prevents unrealistic expectations

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