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doi: 10.1371/journal.pone.0119683 33 XiePXueWQiWLiYYangLYangZet al

The pulsatile GH secretion induced by Tesamorelin remains physiological (preservation of endogenous pulses), distinguishing this approach from exogenous recombinant GH administration producing supra-physiological non-pulsatile levels

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This revelation reveals exciting possibilities in the realm of drug discovery, as GST inhibitors and its prodrugs offer a feasible strategy in designing anticancer drugs with the primary purpose of reversing tumor resistance