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There is evidence that certain gene mutations in cancer can affect the sensitivity to ferroptosis

10.1016/j.jep.2022.115965 75 JorgensenI.MiaoE

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Mitochondria are the primary source of ROS (reactive oxygen species) and RNS (reactive nitrogen species) production and contain approximately 10 to 20% of the total GSH in brain cells and most other organs (65)
