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the endothelium barrier and pump functions should both be recovered to achieve the recovery of corneal swelling and opacity [182,183,184,185,186]

Improved Fat Metabolism (Fat Loss): Supports fat oxidation and improves overall metabolism, leading to reduced body fat mass and better nutrient partitioning

Shi Z, Puyo CA

Despite unpredictable in most cases, the occurrence of AKI is significantly higher in severe I/R injury after kidney transplant surgery, cisplatin for tumor chemotherapy, or contrast media for radiography and so on, especially for the susceptible individuals, including old age and patients with diabetes mellitus or CKD (Zhang et al., 2020)

While targeting glutamine pathwaysparticularly GLS1 and -KG metabolismpresents promising antifibrotic potential, the cell type-specific and compensatory mechanisms highlight the need for precise therapeutic strategies to effectively harness glutamine-targeted interventions in IPF (Fig

Due to its high susceptibility to undergo hyperoxidation even at low levels of oxidative stress its chaperone function is frequently involved in the oxidative folding of various ER resident proteins, likely in cooperation with protein disulfide isomerase (PDI) [68]