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GFP-positive cells were sorted by FACS and expanded in DMEM supplemented with 10% heat-inactivated fetal bovine serum (FBS, Sigma), 100 U ml 1 penicillin and 100 g ml 1 streptomycin (Gibco) at 37 C in a 5% CO 2 incubator 17

To determine the best dosage of MSM to feed to your horse, it is recommended to consult an equine nutritionist or veterinarian

This study was funded by the National Institutes of Health R01MH106563 (P.H.) and the CAMS Lectureship Award (P.H.)

Hepatology 50 , 697706 (2009)

They transfer a methyl group from the methyl donor S-adenosylmethionine (SAM), resulting in 5-methylcytosine (Figure 2)

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