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To further investigate the potential effectiveness of biomolecular nanodisks as a drug-delivery vehicle for CoQ 10 , cultured C2C12 myotubes were treated with supra-pharmacological doses of simvastatin, an HMG-CoA reductase inhibitor that decreases the production of polyprenyl diphosphate precursors, and nanodisk-CoQ 10 [127]

J.2nd (2011)

Though there currently lacks questionnaires differentiating mechanisms causing different subtypes of nociplastic pains (i.e., topdown or bottomup) [12], ongoing efforts have been made to establish and evaluate the types and combinations of features effective in distinguishing nociplastic pains of different mechanisms [209, 218, 265, 271]

Theranostics 13 , 27572773 (2023)

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Figure 1 TEM analysis We used transmission electron microscopy to determine the size and morphology of the synthesized nanoparticles