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Description
Iron overload disrupts mitochondrial metabolism and increases oxidative stress In instances of iron overload, surplus intracellular iron may be transferred to the mitochondria [11]
C., Zamocky M., Lazzarotto F., Margis-PinheiroGoing Forward M
Capture and visualization of hydrogen sulfide by a fluorescent probe
M., Hansen, T
& Medri, M
Mechanistically, the phagocytosis of apoptotic podocyte debris by macrophages triggers the activation of the NLRP3 inflammasome, which in turn promotes the maturation of IL-1 and IL-18, thereby establishing a podocyte-macrophage interactive damage cycle (35)
