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Alpha-lipoic acid also has co-enzyme function and is a component of various enzyme complexes

Zhang N, Zhao B, Fan Z, Yang D, Guo X, Wu Q et al (2020) Systematic identification of genes associated with plant growthdefense tradeoffs under JA signaling in Arabidopsis

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Silybin is not water soluble, however mixing it with other natural products increases its bio-availability and absorption, such as: Berberine The Flavonoid quercetin Healthy fat Vitamin E Bile salts In extract form, youll usually find a combination that brings out milk thistle benefits and enhances absorption to leverage its liver detox properties and antioxidant capabilities