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Although direct evidence for a role of the immune system in the onset of HSCR is absent, RET and its pathway members are expressed by type 3 innate lymphoid cells (ILC3) and are involved in the organogenesis of intestinal Payers patches [60, 61]

For patients in South Florida dealing with chronic UV and heat-related oxidative load year-round, this mechanism is particularly relevant to what we see in our Doral patient population

A.ShahrokhS.ShpichkaA.et al

Illien-Junger, S

Hunter 2013)
