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Manual particle picking was performed on a subset of micrographs belonging to the WT Ycf1 dataset and subject to reference-free 2D Classification to generate references for automated particle picking

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Mosbah H, Vantyghem MC, Nobcourt E et al (2022) Therapeutic indications and metabolic effects of metreleptin in patients with lipodystrophy syndromes: real-life experience from a national reference network

They may even stop glutathione production altogether

Introduction All organisms maintain a strict redox environment, crucial for cell physiology, by preserving the pro-oxidant compounds generated during cell metabolism and from antioxidant system elements

Tissues can contain tens to thousands of copies of mtDNA per cell, depending on cell type