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Clin Endocrinol (Oxf) 57: 577-585 Wekking EM, Appelhof BC, Fliers E, Schene AH, Huyser J, et al

TMAO is believed to promote NAFLD through four pathways: enhancing oxidative stress (Li X

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Research has shown that BAs in combination with its activating transcription factor, farnesoid X receptor (FXR), inhibit cholesterol transport and increase cholesterol excretion by macrophages in order to reduce cholesterol concentration in plasma, and can be used as a therapeutic target for dyslipidemia (Figure 2

Parsa H, Zangivand AA, Hajimaghsoudi L

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