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doi: 10.1016/j.phrs.2004.08.006

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Magnesium: One study found that birth control may lead to lower levels of minerals like magnesium [21], and symptoms of magnesium deficiency include fatigue and muscle cramps [29]

& Slevogt, H

110 Chemical modifications, particularly PEGylation, have been widely employed to enhance the pharmaceutical properties of peptides, improving their solubility, structural stability, and overall therapeutic potential

Some protocols add 0.6% acetic acid for better solubility
