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subsequently documented that KO of Nrf2 enhances ROS production and exaggerates cell death in cultured adult cardiomyocytes in a setting of high glucose-induced oxidative stress (Sussan et al

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J Biol Chem 292:47664769 Cordes T, Lucas A, Divakaruni AS, Murphy AN, Cabrales P, Metallo CM (2020) Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury

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