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Description
Dynamin-related protein 1 (Drp1) is a protein responsible for the fission of the mitochondrial outer membrane

92 , e0042223 (2024)

Tubular epithelial cells undergo -catenin-driven EMT via Twist1/Zeb1 upregulation and excessive extracellular matrix (ECM) production (collagen I/IV, fibronectin), correlating with rapid eGFR decline in human biopsies (3.5-fold higher nuclear -catenin in progressive DKD)
Additionally, we extend our thanks to the Curie English Editing Service, by American Journal Experts (AJEs) for their support in refining the manuscript

[Google Scholar] Millotti G, Perera G, Vigl C, Pickl K, Sinner FM, Bernkop-Schnurch A
These conditions directly and rapidly affect cellular redox balance and induce an increase in ROS with consequences at multiple levels, including rapid protein oxidation [247]