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A., Sparks, S

These are 4-year terms.

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In that proposed mechanism, unconjugated bile acids in bile becomes pronated and are passively absorbed by the biliary epithelial cells (cholangiocytes)

Within the TME, high CHKA expression in tumor cells transforms them into metabolic choline sinks, depriving nearby immune cells, such as tumor-infiltrating lymphocytes (TILs), of choline needed for their own membrane synthesis, thereby contributing to immunosuppression (Li et al., 2025)

Acrolein produced during acute kidney injury promotes tubular cell death
