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In MPP + -induced MES23.5 dopaminergic cells, astrocytes increase ferritin release in response to iron overload to protect DA neurons (Zhang et al., 2022)

2 Lipid peroxidation and acetaminophen-induced cell death

[DOI] [PubMed] [Google Scholar] 171.Tsujiuchi T., Tsutsumi M., Sasaki Y., Takahama M., Konishi Y

As of writing, 5-amino-1MQ is not approved for human use but is available as a research chemical for laboratory experimentation

513 NMNAT, as a binding partner of HSP90, can specifically recognize p-Tau to inhibit its amyloid aggregation in vitro and reduce its symptoms in the fly tauopathy model, and this effect could be competitively destroyed by its enzymatic substrate