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The reaction is a transamination in which the -amino group is transferred to the -keto carbon of 2-oxoglutarate (-ketoglutarate) forming the metabolite, saccharopine

doi: 10.13652/j.spjx.1003.5788.2023.80342 541 GuoXTresserra-RimbauAEstruchRMartnez-GonzlezMAMedina-RemnAFitMet al

10.1016/j.nbd.2006.10.008

Neuroinflammation disrupts the neuronal microenvironment, interfering with drug action and accelerating the aggregation of alpha-synuclein 73
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