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Role in cell protection and aging-related vulnerability to neurodegeneration

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In vitro enzyme activity assays of recombinant FNSII proteins To investigate the enzymatic properties of LjFNSII and LmFNSII proteins, the microsomes were prepared from transformed yeast cells

3.3 Ketogenic diet The ketogenic diet (KD) is characterized by very low-carbohydrate and high-fat, which induces a metabolic shift and elevates circulating ketone bodies (Ang et al., 2020)

When intracellular Fe 2+ is abundant, Fur binds Fe 2+ as a co-repressor and dimerizes, enabling it to recognize the Fur box in target promoters

The specific factors and pathways regulating cellular differentiation, migration, spatial and morphogenic patterns and neurological development, involved in the physiopathology of neurodevelopmental disorders and mitochondriopathies, are not recapitulated in 2D cell cultures