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Cerebral perfusion and metabolic response of astrocytes and neurons during locomotion

Tikhomirova, I

Furthermore, supplementation with TCA cycle intermediates -KG and succinate reversed the rescue effect of anaplerosis inhibition and induced lipid peroxidation-driven cell death, even in CAMA-1 cells, which are otherwise resistant to cystine deprivation, suggesting that differential sensitivity between TNBC and luminal cells may stem from their distinct glutamine metabolic flux

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doi: 10.1016/S0140-6736(18)32752-1

Together, these results suggest that pomegranates exert strong anxiolytic-like action when a stressor triggers the state of anxiety