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The glutathione peroxidase (GPx) mimetic activity of all the selenium compounds showed significantly by facilitating the oxidation of the selenium centre

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Isoniazid (the hydrazide derivative of isonicotinic acid) was, at one time, a primary drug for chemotherapeutic treatment of tuberculosis but is now used in a cocktail of four antibiotics referred to as RIPE therapy (rifampin, isoniazid, pyrazinamide, and ethambutol)

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