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Description
Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation
NNMT's job: Take nicotinamide (a NAD+ precursor) and methylate it essentially tagging it for disposal
the risk is lower than after malabsorptive procedures as no bowel is bypassed
NDC: 70069-0005-10
What is vitamin B12, and why is it essential
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