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IL-8 is pivotal in modulating essential metabolic and cellular development pathways, specifically RAS/MEK/ERK and PI3K/Akt, and is crucial in the progression of MDR in ovarian cancer cells
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Nat Cell Biol 8:10641073 Brenkman AB, de Keizer PL, van den Broek NJ, Jochemsen AG, Burgering BM (2008) Mdm2 induces mono-ubiquitination of FOXO4
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