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In patients with Stanford type A aortic dissection, iron levels and the lipid peroxidation product 4-HNE were increased in the aorta, while key ferroptosis regulatory proteins, including SLC7A11, GPX4, and FSP1 were downregulated

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Drugs such as DFOM and deferiprone can chelate iron and thereby inhibit ferroptosis

P.LangI.BoerK.BondarenkoI

S.AltmanB
