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[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Luetic K., Sucic M., Vlainic J., Halle Z.B., Strinic D., Vidovic T., Luetic F., Marusic M., Gulic S., Turudic Pavelic T., et al

As a result, CSF dopamine levels do not accurately indicate CNS dopamine deficiency Simultaneously, although changes in HVA in the striatum are not fully consistent with dopamine levels, DOPAC is a major metabolite of dopamine, suggesting that DOPAC in the CSF is more suitable for use as a diagnostic indicator of PD than dopamine and HVA (Landau et al., 2022)

Initial report of human cytochrome P450 was in 1960s (Reynolds, 1966) and the first human CYP isoform was cloned in 1985 (actually a partial cloning of human CYP2A6) (Phillips et al., 1985)

DOI 10.1016/0149-7634(84)90022-8 Graf MV, Kastin AJ

For DTT treatment, a 5 mM DTT solution was used for 24 h treatment