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Bibcode:2018PLoSO..1302360J

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Dysregulation of Astrocytic Glutamate Uptake and/or Release Leads to CNS Disorders Under normal conditions, glutamate in the extracellular space must be maintained at very low concentrations to prevent overexcitation of glutamate receptors in neurons and protect against neuronal excitotoxicity

Dhanda, G., Acharya, Y

These data suggests there may be a sensor that sets the ELF GSH adaptive response to prevent GSH levels from dipping below basal levels