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Neuroinflammation was also reduced, judging from lower levels of inflammatory markers, which included the microglial marker Iba1 and pathways associated with microglial activation

doi: 10.1002/art.24266
SB216763, on the other hand, upregulates sulfenic acid modification at more than 40 unique sites including PRDX6, indicating that GSK3 inhibition produces more targeted changes in cysteine oxidation than might be expected from non-specific diffusion of H 2 O 2 throughout the cell
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In the same studies, enzyme activities of catalase and SOD were significantly lower in islets from mice than in humans