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Isatuximab was originally developed for its ability to operate via CDC, while Daratumumab was selected to enhance ADCC activity

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Finally, for encephalopathies therapy (see Chapter Nerve-Nerve), acting simultaneously in both the periphery and central nervous system, BPC 157 counteracted various encephalopathies and stomach and liver lesions in non-steroidal anti-inflammatory drugs (NSAIDs)-rats [61,105,106,107,108,109] and insulin-rats [62]

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Salinas RA, Alvarez G, Daly F, Ferreira J