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Martinelli C, Pucci C, Battaglini M, Marino A, Ciofani G

The relative levels of different enzymes and substrates will influence the overall composition of the membrane, thereby affecting the cells sensitivity to ferroptosis

For example, as a pioneer factor, Oct4 can loosen heterochromatin and reduce the global levels of inhibitory H3K9me2, H3K9me3, and 5-methylcytosine, 326 which are obstacles in reprogramming

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Changmin Lee 2 (Professor)

The K1 thyroid cancer cells (1.5 10 5 ) were treated with RSL3 (3 M), Fer1 (5 M) or DMSO control for 3.5 h
