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Biomarkers related to DNA damage by ROS in CKD patients include 8-hydroxydeoxyguanosine (8-OH-dG) and 8-oxodeoxyguanosine (8-oxo-dG)

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As Met load usually leads to high Hcy and cardiovascular effects, Selhub and Troen designed a study to determine if increased Met intake is atherogenic (221)