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Therefore, NAC can promote the synthesis of GSH and replenish the antioxidant system, and plays a role in GSH depletion conditions, such as acetaminophen or organophosphate poisoning ( While NAC effectively replenishes GSH in GSH-deficient conditions, its ability to increase GSH levels under normal conditions is generally limited ( 2.2 Direct ROS scavenger NAC is a thiol compound that exhibits a high propensity for reacting with oxidants from a chemical thermodynamic perspective

Hepatitis C virus: from oxygen free radicals to hepatocellular carcinoma

Arteriosclerosis Thrombosis and Vascular Biology , 1997, 17:2074-81

Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through s-nitrosylation and inhibition of bcl-2 ubiquitination

1), accounting for an estimated 90% of crypt or villus cells (Mu et al