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A: Observational research suggests that people taking GLP-1 receptor agonists may have a lower risk of developing substance use disorders, but clinical trials are needed to confirm whether these drugs directly influence addiction

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We need more targeted studies on low-dose and microdose effects, but the clinical signals are encouraging

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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Mann JFE, et al

When a T cell with PD-1 on its surface interacts with another cell which has a PD-1 ligand (PD-L1), the T-cell activity is down-regulated