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Schwartz DM, Bonelli M, Gadina M, OShea JJ (2016) Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases

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This protection reduces oxidative stress, which is linked to aging and many chronic health conditions

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E2 deficiency downregulates the Er-PGC-1-NRF1 transcriptional axis, leading to suppressed SOD2 expression and impaired clearance of mitochondrial ROS, initiating a vicious cycle of oxidative damage and mitochondrial destabilization (122)

Vansiton L-Carnitine +Coenzyme Q10 % : 2-3 40