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doi: 10.3390/healthcare11131946

A multicenter trial of 390 patients with diabetes mellitus receiving insulin therapy who were randomized to receive metformin, 850 mg three times daily, or placebo assessed the risk of vitamin B 12 deficiency and low vitamin B 12 levels over four years

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B12 Injections & Neuropathy: How They Help When administered through injections injected intramuscularly and perineurally (near the affected nerve areas) Vitamin B12 supports: 1

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This typically improves over time as the body adjusts