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Published clinical trials used continuous daily administration for 12-24 weeks without scheduled breaks, establishing this as a viable approach with maintained safety throughout the treatment period

5 million cells were used for the GSH assay after lysing by sonication (20 kHz, 70% amplitude, 2 10 s)

Heat can be used to disrupt hydrogen bonds and non-polar hydrophobic interactions

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Cancer Res, 58, 25682575

Regulation of glutaminase activity and glutamine metabolism