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We will focus on the mechanisms directly related to receptor regulation such as down-regulation, G protein uncoupling, desensitization, and internalization

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On the basis of differences in genomic homology, host range of infection, replication efficiency, latent cell species, and pathogenicity, the herpesvirus family is divided into the Alphaherpesvirinae (), Betaherpesvirinae (), and Gammaherpesvirinae () subfamilies by the International Commission on Taxonomy of Viruses (ICTV

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