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The inability to acquire cysteine through xCT may force cancer cells to use the TSS pathway, less common extracellular dipeptides, or extracellular glutathione to produce cysteine for proliferation [5,30,50,91]
Hence, the steady-state response is a sinusoidal oscillation about a constant mean value y mean with an amplitude ratio (output amplitude/input amplitude) given by | G ( i *)|
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"Developmental programming of CpG island methylation profiles in the human genome"
