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(2019) "Structure-activity relationship for NNMT inhibitors." Published in Biochemical Pharmacology

5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor studied for its effects on NAD+ metabolism, cellular energy regulation, and adipose tiss It is supplied for laboratory research use only

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Third, they found that the enzymatic activity of NNMT is necessary for the increase in Sirt1 protein expression and a product of NNMT (MNA) plays a key role [14]

Both produce weight loss
