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That's the real reason this molecule gets so much attention

April 25, 2025

These enzymes break down collagen and extracellular matrix

(1995) Analysis of responses to ANG IV: effects of PD-123319 and DuP-753 in the pulmonary circulation of the rat

Clinical cohort analysis of germline EGFR T790M demonstrates penetrance across ethnicities and races, sexes, and ages

This leads to inflammation in the lining of the joints (synovium), causing painful swelling that can eventually result in bone erosion and joint deformity
