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The presence of LPS induces an increase of neutrophils, macrophages, and cytokines in sputum and bronchoalveolar lavage fluid (BALF) and induces an increase of ROS [56]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 262.Wu Y., Sun B., Tang Y., Shen A., Lin Y., Zhao X., Li J., Monteiro M.J., Gu W

At 10 mg/mL : The top two rungs exceed a single 100-unit barrel, so at 12.5 and 15 mg the volume must be split across two injections or the vial reconstituted at a higher concentration with less water

Decreases free radical production in the brain

The convergence of these mechanisms is reflected in the significant alleviation of core ASD symptoms (e.g., improved social interaction and language communication, decreased repetitive/compulsive behaviors), co-morbid GI distress, sleep disorders, and a measurable reduction in systemic inflammation and standardized behavioral scores (e.g., ABC, CARS) (Kang et al., 2017