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GSH-conjugated 4-HNE is an inhibitor of GST, among other biological activities, and must therefore be exported from cells, a process likely mediated by MRP1 (78)

Optimizing drug administration regimens, determining the optimal timing and sequence of treatments, managing potential adverse reactions, and ultimately designing rational clinical trials for translation represent an area that requires further exploration

doi: 10.1016/j.amepre.2015.02.009

Over time, the skin begins to show signs of ageing due to exposure to pollutants, sun damage, and the natural ageing process

Thus, there are proteins in the center of the adult lens that were synthesized prior to birth
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