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Graber MD Updated: October 22nd 2022 Main Source of Information: Empower Overview of Methylcobalamin (B12) Injection General Information Methylcobalamin, or vitamin B12, is a B-vitamin

Several RNAi drugs, including aptamers like pegaptanib targeting protein targets, and micro interfering RNAs like givosiran and patisiran, as well as antisense oligonucleotides like golodirsen and inotersen that interfere directly with RNA targets, have received FDA approval for medical use (Yu et al., 2020)

Another strategy involves the use of PARP inhibitor BGP-15, which might protect against CC, to enhance mitochondrial homeostasis 260,261

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Supplementation may help improve mood and reduce symptoms of depression, particularly in those with B12 deficiency