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JCI Insight 6 , e137761 (2021)

(January 2013)

doi: 10.3389/fnmol.2018.00320 270 McKenzieBAMamikMKSaitoLBBoghozianRMonacoMCMajorEOet al
Iron acts as a cofactor in the production of ROS and hastens oxidative damage that attacks cellular DNA, proteins, and membranes, especially the internal mitochondrial membrane where the electron transport chain reaction takes place 84

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