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Our assay is the first microtiter plate procedure that has been developed and validated for measurement of both GSH and GSSG in the liver tissue, in addition to the bile samples

Author Contributions Gholamreza Abdi : Conceptualized the chapter, provided supervision, and led the writing and critical revision process, and writingoriginal draft

6.5.1 Technological innovations in exposure assessment 6.5.1.1 Advanced analytical technologies Single-cell omics approaches enable detection of EED-induced epigenetic changes in individual sperm cells, providing unprecedented precision in exposure assessment ( 6.5.2 Development of targeted therapeutic interventions 6.5.2.1 Molecular-level interventions CRISPR/dCas9-based epigenetic correction represents a promising strategy for reversing EED-induced DNA methylation changes that compromise reproductive function ( 6.5.3 Strengthening international collaboration 6.5.3.1 Global policy coordination Harmonization of international regulatory standards for EED exposure limits and biomonitoring protocols remains essential for effective global health protection ( The integration of technological innovation, policy development, and individual-level interventions offers the greatest promise for effectively mitigating EED-related reproductive health risks and protecting future generations from environmental endocrine disruption

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Incretin signaling at the crossroads of metabolism, inflammation, and tumorigenesis: implications for obesity patients