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The cycle length and dosing schedule are individualized based on patient response and goals

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Ectopic lesions show significant volumetric regression, while systemic and local production of key pathological mediators, including tumor necrosis factor-alpha (TNF-), vascular endothelial growth factor (VEGF), and matrix metalloproteinase-2 (MMP-2), is markedly reduced

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Recognizing these limitations, clinical practice has increasingly shifted away from restricted SNP panels toward what is widely considered one of the most cost-effective strategies to date: whole-exome sequencing (WES