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Additionally, three smaller clinical studies reported -tocopherol did not improve hematological parameters or patient outcome [54,57,58] (Table 2)

Fatigue is a central feature of all these disorders, often exacerbated by exertion and non-restorative sleep

The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)

doi: 10.1038/nrn2303

What Is BPC-157, and How Does It Work

Questions also remain in the biomedical context