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Over the past few years, among the substances that could potentially be used for migraine treatment, particular attention has been paid to the so-called nutraceutics, including antioxidants

D-galactose induces damage to hippocampal neurons by increasing ROS production and advanced glycation end product accumulation, leading to oxidative stress, mitochondrial dysfunction, and neuroinflammation

Administration of high concentrations of sodium selenite preferentially targets and eradicates cancer cells because more free radicals are produced than in normal cells and no systemic selenotoxicity is produced (130)

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