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a safe, endogenous (non-toxic) transport mechanism called receptor-mediated endocytosis therapeutic moieties such as large proteins and liposomes containing drugs and genes, i.e

doi: 10.1016/j.biocel.2014.02.020

Furthermore, resveratrol was well tolerated, with no serious adverse effects reported [211]

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In this complex microenvironment, the hepatic immune system tolerates harmless molecules while at the same time remaining alert to possible infectious agents, malignant cells or tissue damage

Although NO has an anti-inflammatory effect under normal physiological conditions, it is a pro-inflammatory mediator that induces inflammation due to over production in abnormal situations